The ATF2 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to ATF2, and mXBP. This antibody recognizes Human, and Mouse antigen. The ATF2 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain